make has 69 distinct synonyms spread across 28 of its 51 senses. Each sense below keeps its own list, because a synonym belongs to a meaning and not to a word: swapping one sense's substitute into another sense's sentence is how a thesaurus makes writing worse. Its 2 recorded opposites are unmake, break.
Counts are distinct word forms across every sense. A synonym that appears under three senses is counted once here and shown three times below, under each sense it belongs to.
create or manufacture a man-made product
“We produce more cars than we can sell”
make, formulate, or derive in the mind
“I draw a line here”
to compose or represent
“This wall forms the background of the stage setting”
be or be capable of being changed or made into
“He makes a great host”
make by shaping or bringing together constituents
“make a dress”
change from one form into another
“make water into wine”
act in a certain way so as to acquire
“make friends”
carry out or commit
“make a mistake”
form by assembling individuals or constituents
“Make a quorum”
have a bowel movement
“The dog had made in the flower beds”
undergo fabrication or creation
“This wool makes into a nice sweater”
be suitable for
“Wood makes good furniture”
amount to
“This salary increase makes no difference to my standard of living”
constitute the essence of
“Clothes make the man”
appear to begin an activity
“He made to speak but said nothing in the end”
reach in time
“We barely made the plane”
gather and light the materials for
“make a fire”
represent fictitiously, as in a play, or pretend to be or act like
“She makes like an actress”
consider as being
“It wasn't the problem some people made it”
calculate as being
“I make the height about 100 feet”
cause to be enjoyable or pleasurable
“make my day”
favor the development of
“Practice makes the winner”
develop into
“He will make a splendid father!”
eliminate urine
“Again, the cat had made on the expensive rug”
the act of mixing cards haphazardly
Synonyms, antonyms and the broader and narrower relations for make come from Princeton University’s WordNet. Full sources and licences.