frame has 34 distinct synonyms spread across 12 of its 18 senses. Each sense below keeps its own list, because a synonym belongs to a meaning and not to a word: swapping one sense's substitute into another sense's sentence is how a thesaurus makes writing worse. WordNet records no antonym for it — antonymy is a relation between word forms rather than concepts, so it is deliberately sparse.
Counts are distinct word forms across every sense. A synonym that appears under three senses is counted once here and shown three times below, under each sense it belongs to.
a single one of a series of still transparent pictures forming a cinema, television or video film
alternative names for the body of a human being
“Leonardo studied the human body”
an application that divides the user's display into two or more windows that can be scrolled independently
a system of assumptions and standards that sanction behavior and give it meaning
the hard structure (bones and cartilages) that provides a frame for the body of an animal
the internal supporting structure that gives an artifact its shape
“the building has a steel skeleton”
one of the ten divisions into which bowling is divided
Synonyms, antonyms and the broader and narrower relations for frame come from Princeton University’s WordNet. Full sources and licences.