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isabella the catholic has 3 distinct synonyms spread across 1 of its 1 sense. Each sense below keeps its own list, because a synonym belongs to a meaning and not to a word: swapping one sense's substitute into another sense's sentence is how a thesaurus makes writing worse. WordNet records no antonym for it — antonymy is a relation between word forms rather than concepts, so it is deliberately sparse.
Counts are distinct word forms across every sense. A synonym that appears under three senses is counted once here and shown three times below, under each sense it belongs to.
the queen of Castile whose marriage to Ferdinand of Aragon in 1469 marked the beginning of the modern state of Spain; they instituted the Spanish Inquisition in 1478 and sponsored the voyages of Christopher Columbus in 1492 (1451-1504)
Synonyms, antonyms and the broader and narrower relations for isabella the catholic come from Princeton University’s WordNet. Full sources and licences.