queen has 16 distinct synonyms spread across 5 of its 12 senses. Each sense below keeps its own list, because a synonym belongs to a meaning and not to a word: swapping one sense's substitute into another sense's sentence is how a thesaurus makes writing worse. Its one recorded opposite is king.
Counts are distinct word forms across every sense. A synonym that appears under three senses is counted once here and shown three times below, under each sense it belongs to.
the wife or widow of a king
something personified as a woman who is considered the best or most important of her kind
“Paris is the queen of cities”
one of four face cards in a deck bearing a picture of a queen
an especially large mole rat and the only member of a colony of naked mole rats to bear offspring which are sired by only a few males
promote to a queen, as of a pawn in chess
Synonyms, antonyms and the broader and narrower relations for queen come from Princeton University’s WordNet. Full sources and licences.