instruction has 9 distinct synonyms spread across 4 of its 4 senses. Each sense below keeps its own list, because a synonym belongs to a meaning and not to a word: swapping one sense's substitute into another sense's sentence is how a thesaurus makes writing worse. WordNet records no antonym for it — antonymy is a relation between word forms rather than concepts, so it is deliberately sparse.
Counts are distinct word forms across every sense. A synonym that appears under three senses is counted once here and shown three times below, under each sense it belongs to.
a message describing how something is to be done
“he gave directions faster than she could follow them”
the activities of educating or instructing; activities that impart knowledge or skill
“he received no formal education”
the profession of a teacher
“he prepared for teaching while still in college”
(computer science) a line of code written as part of a computer program
Synonyms, antonyms and the broader and narrower relations for instruction come from Princeton University’s WordNet. Full sources and licences.