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Syllable division and stress derived from spelling — this word is not in the pronouncing dictionary, so no phonetic transcription is shown rather than a guessed one.
mephistophelean is an adjective meaning "showing the cunning or ingenuity or wickedness typical of a devil". It carries one recorded sense.
showing the cunning or ingenuity or wickedness typical of a devil
“devilish schemes”
“the cold calculation and diabolic art of some statesmen”
“the diabolical expression on his face”
“a mephistophelian glint in his eye”
Definitions, synonyms and semantic relations for mephistophelean come from Princeton University’s WordNet. Commonness is measured against a corpus of everyday English. Full sources and licences.