say it: an-tag-uh-NI-stik
antagonistic is an adjective meaning "indicating opposition or resistance". It carries 5 recorded senses.
characterized by antagonism or antipathy
“slaves antagonistic to their masters”
“antipathetic factions within the party”
arousing animosity or hostility
“his antagonistic brusqueness”
“Europe was antagonistic to the Unites States”
used especially of drugs or muscles that counteract or neutralize each other's effect
incapable of harmonious association
Definitions, synonyms and semantic relations for antagonistic come from Princeton University’s WordNet. The pronunciation comes from the CMU Pronouncing Dictionary. Commonness is measured against a corpus of everyday English. Full sources and licences.