wipeout has 2 distinct synonyms spread across 1 of its 2 senses. Each sense below keeps its own list, because a synonym belongs to a meaning and not to a word: swapping one sense's substitute into another sense's sentence is how a thesaurus makes writing worse. WordNet records no antonym for it — antonymy is a relation between word forms rather than concepts, so it is deliberately sparse.
Counts are distinct word forms across every sense. A synonym that appears under three senses is counted once here and shown three times below, under each sense it belongs to.
an event (or the result of an event) that completely destroys something
Synonyms, antonyms and the broader and narrower relations for wipeout come from Princeton University’s WordNet. Full sources and licences.
a spill in some sport (as a fall from a bicycle or while skiing or being capsized on a surfboard)