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vertebrate has 1 distinct synonym spread across 1 of its 2 senses. Each sense below keeps its own list, because a synonym belongs to a meaning and not to a word: swapping one sense's substitute into another sense's sentence is how a thesaurus makes writing worse. Its one recorded opposite is invertebrate.
Counts are distinct word forms across every sense. A synonym that appears under three senses is counted once here and shown three times below, under each sense it belongs to.
having a backbone or spinal column
“fishes and amphibians and reptiles and birds and mammals are verbetrate animals”
Synonyms, antonyms and the broader and narrower relations for vertebrate come from Princeton University’s WordNet. Full sources and licences.