spirit has 17 distinct synonyms spread across 7 of its 9 senses. Each sense below keeps its own list, because a synonym belongs to a meaning and not to a word: swapping one sense's substitute into another sense's sentence is how a thesaurus makes writing worse. WordNet records no antonym for it — antonymy is a relation between word forms rather than concepts, so it is deliberately sparse.
Counts are distinct word forms across every sense. A synonym that appears under three senses is counted once here and shown three times below, under each sense it belongs to.
the vital principle or animating force within living things
any incorporeal supernatural being that can become visible (or audible) to human beings
the state of a person's emotions (especially with regard to pleasure or dejection)
“his emotional state depended on her opinion”
animation and energy in action or expression
“it was a heavy play and the actors tried in vain to give life to it”
an inclination or tendency of a certain kind
“he had a change of heart”
Synonyms, antonyms and the broader and narrower relations for spirit come from Princeton University’s WordNet. Full sources and licences.