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spindle has 4 distinct synonyms spread across 2 of its 5 senses. Each sense below keeps its own list, because a synonym belongs to a meaning and not to a word: swapping one sense's substitute into another sense's sentence is how a thesaurus makes writing worse. WordNet records no antonym for it — antonymy is a relation between word forms rather than concepts, so it is deliberately sparse.
Counts are distinct word forms across every sense. A synonym that appears under three senses is counted once here and shown three times below, under each sense it belongs to.
(biology) tiny fibers that are seen in cell division; the fibers radiate from two poles and meet at the equator in the middle
“chromosomes are distributed by spindles in mitosis and meiosis”
a piece of wood that has been turned on a lathe; used as a baluster, chair leg, etc.
Synonyms, antonyms and the broader and narrower relations for spindle come from Princeton University’s WordNet. Full sources and licences.
any of various rotating shafts that serve as axes for larger rotating parts
a stick or pin used to twist the yarn in spinning
any holding device consisting of a rigid, sharp-pointed object
“the spike pierced the receipts and held them in order”