smoke has 18 distinct synonyms spread across 7 of its 10 senses. Each sense below keeps its own list, because a synonym belongs to a meaning and not to a word: swapping one sense's substitute into another sense's sentence is how a thesaurus makes writing worse. WordNet records no antonym for it — antonymy is a relation between word forms rather than concepts, so it is deliberately sparse.
Counts are distinct word forms across every sense. A synonym that appears under three senses is counted once here and shown three times below, under each sense it belongs to.
a hot vapor containing fine particles of carbon being produced by combustion
“the fire produced a tower of black smoke that could be seen for miles”
an indication of some hidden activity
“with all that smoke there must be a fire somewhere”
something with no concrete substance
“his dreams all turned to smoke”
tobacco leaves that have been made into a cylinder
inhale and exhale smoke from cigarettes, cigars, pipes
“We never smoked marijuana”
Synonyms, antonyms and the broader and narrower relations for smoke come from Princeton University’s WordNet. Full sources and licences.