simplify has no recorded synonym. Each sense below keeps its own list, because a synonym belongs to a meaning and not to a word: swapping one sense's substitute into another sense's sentence is how a thesaurus makes writing worse. Its one recorded opposite is complicate.
Counts are distinct word forms across every sense. A synonym that appears under three senses is counted once here and shown three times below, under each sense it belongs to.
make simpler or easier or reduce in complexity or extent
“We had to simplify the instructions”
Synonyms, antonyms and the broader and narrower relations for simplify come from Princeton University’s WordNet. Full sources and licences.