shot has 25 distinct synonyms spread across 14 of its 18 senses. Each sense below keeps its own list, because a synonym belongs to a meaning and not to a word: swapping one sense's substitute into another sense's sentence is how a thesaurus makes writing worse. WordNet records no antonym for it — antonymy is a relation between word forms rather than concepts, so it is deliberately sparse.
Counts are distinct word forms across every sense. A synonym that appears under three senses is counted once here and shown three times below, under each sense it belongs to.
a solid missile discharged from a firearm
“the shot buzzed past his ear”
(sports) the act of swinging or striking at a ball with a club or racket or bat or cue or hand
“it took two strokes to get out of the bunker”
a person who shoots (usually with respect to their ability to shoot)
“he is a crack shot”
a consecutive series of pictures that constitutes a unit of action in a film
the act of putting a liquid into the body by means of a syringe
“the nurse gave him a flu shot”
a small drink of liquor
“he poured a shot of whiskey”
an estimate based on little or no information
an informal photograph; usually made with a small hand-held camera
“my snapshots haven't been developed yet”
sports equipment consisting of a heavy metal ball used in the shot put
“he trained at putting the shot”
a blow hard enough to cause injury
“he is still recovering from a shot to his leg”
an attempt to score in a game
the launching of a missile or spacecraft to a specified destination
varying in color when seen in different lights or from different angles
“changeable taffeta”
Synonyms, antonyms and the broader and narrower relations for shot come from Princeton University’s WordNet. Full sources and licences.