sharpen has 6 distinct synonyms spread across 3 of its 8 senses. Each sense below keeps its own list, because a synonym belongs to a meaning and not to a word: swapping one sense's substitute into another sense's sentence is how a thesaurus makes writing worse. Its 3 recorded opposites are dull, soften, flatten.
Counts are distinct word forms across every sense. A synonym that appears under three senses is counted once here and shown three times below, under each sense it belongs to.
make crisp or more crisp and precise
“We had to sharpen our arguments”
become sharp or sharper
“The debate sharpened”
make (images or sounds) sharp or sharper
Synonyms, antonyms and the broader and narrower relations for sharpen come from Princeton University’s WordNet. Full sources and licences.