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reaction has 2 distinct synonyms spread across 2 of its 7 senses. Each sense below keeps its own list, because a synonym belongs to a meaning and not to a word: swapping one sense's substitute into another sense's sentence is how a thesaurus makes writing worse. WordNet records no antonym for it — antonymy is a relation between word forms rather than concepts, so it is deliberately sparse.
Counts are distinct word forms across every sense. A synonym that appears under three senses is counted once here and shown three times below, under each sense it belongs to.
(chemistry) a process in which one or more substances are changed into others
“there was a chemical reaction of the lime with the ground water”
Synonyms, antonyms and the broader and narrower relations for reaction come from Princeton University’s WordNet. Full sources and licences.
an idea evoked by some experience
“his reaction to the news was to start planning what to do”
a bodily process occurring due to the effect of some antecedent stimulus or agent
“a bad reaction to the medicine”
(mechanics) the equal and opposite force that is produced when any force is applied to a body
“every action has an equal and opposite reaction”
a response that reveals a person's feelings or attitude
“he was pleased by the audience's reaction to his performance”
extreme conservatism in political or social matters
“the forces of reaction carried the election”
doing something in opposition to another way of doing it that you don't like
“his style of painting was a reaction against cubism”