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predetermination has 3 distinct synonyms spread across 1 of its 3 senses. Each sense below keeps its own list, because a synonym belongs to a meaning and not to a word: swapping one sense's substitute into another sense's sentence is how a thesaurus makes writing worse. WordNet records no antonym for it — antonymy is a relation between word forms rather than concepts, so it is deliberately sparse.
(theology) being determined in advance; especially the doctrine (usually associated with Calvin) that God has foreordained every event throughout eternity (including the final salvation of mankind)
a mental determination or resolve in advance; an antecedent intention to do something
Synonyms, antonyms and the broader and narrower relations for predetermination come from Princeton University’s WordNet. Full sources and licences.
Counts are distinct word forms across every sense. A synonym that appears under three senses is counted once here and shown three times below, under each sense it belongs to.
“he entered the argument with a predetermination to prove me wrong”
the act of determining or ordaining in advance what is to take place