pickup has 6 distinct synonyms spread across 5 of its 9 senses. Each sense below keeps its own list, because a synonym belongs to a meaning and not to a word: swapping one sense's substitute into another sense's sentence is how a thesaurus makes writing worse. WordNet records no antonym for it — antonymy is a relation between word forms rather than concepts, so it is deliberately sparse.
Counts are distinct word forms across every sense. A synonym that appears under three senses is counted once here and shown three times below, under each sense it belongs to.
a light truck with an open body and low sides and a tailboard
a warrant to take someone into custody
“put out a pickup on that man”
Synonyms, antonyms and the broader and narrower relations for pickup come from Princeton University’s WordNet. Full sources and licences.
anything with restorative powers
“she needed the pickup that coffee always gave her”
a casual acquaintance; often made in hope of sexual relationships
the attribute of being capable of rapid acceleration
“his car has a lot of pickup”
mechanical device consisting of a light balanced arm that carries the cartridge
an electro-acoustic transducer that is the part of the arm of a record player that holds the needle and that is removable
the act or process of picking up or collecting from various places
“garbage pickup is on Mondays and Thursdays”
the act of taking aboard passengers or freight