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madness has 12 distinct synonyms spread across 5 of its 5 senses. Each sense below keeps its own list, because a synonym belongs to a meaning and not to a word: swapping one sense's substitute into another sense's sentence is how a thesaurus makes writing worse. WordNet records no antonym for it — antonymy is a relation between word forms rather than concepts, so it is deliberately sparse.
Counts are distinct word forms across every sense. A synonym that appears under three senses is counted once here and shown three times below, under each sense it belongs to.
an acute viral disease of the nervous system of warm-blooded animals (usually transmitted by the bite of a rabid animal); rabies is fatal if the virus reaches the brain
the quality of being rash and foolish
“trying to drive through a blizzard is the height of folly”
Synonyms, antonyms and the broader and narrower relations for madness come from Princeton University’s WordNet. Full sources and licences.