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life-support system has 1 distinct synonym spread across 2 of its 2 senses. Each sense below keeps its own list, because a synonym belongs to a meaning and not to a word: swapping one sense's substitute into another sense's sentence is how a thesaurus makes writing worse. WordNet records no antonym for it — antonymy is a relation between word forms rather than concepts, so it is deliberately sparse.
Counts are distinct word forms across every sense. A synonym that appears under three senses is counted once here and shown three times below, under each sense it belongs to.
equipment that makes life possible in otherwise deadly environmental conditions
“the astronauts relied on their life-support systems”
medical equipment that assists or replaces important bodily functions and so enables a patient to live who otherwise might not survive
“the patient is on life support”
Synonyms, antonyms and the broader and narrower relations for life-support system come from Princeton University’s WordNet. Full sources and licences.