kill has 16 distinct synonyms spread across 5 of its 18 senses. Each sense below keeps its own list, because a synonym belongs to a meaning and not to a word: swapping one sense's substitute into another sense's sentence is how a thesaurus makes writing worse. WordNet records no antonym for it — antonymy is a relation between word forms rather than concepts, so it is deliberately sparse.
Counts are distinct word forms across every sense. A synonym that appears under three senses is counted once here and shown three times below, under each sense it belongs to.
be the source of great pain for
“These new shoes are killing me!”
overwhelm with hilarity, pleasure, or admiration
“The comedian was so funny, he was killing me!”
hit with so much force as to make a return impossible, in racket games
“She killed the ball”
hit with great force
“He killed the ball”
deprive of life
“AIDS has killed thousands in Africa”
cause the death of, without intention
“She was killed in the collision of three cars”
mark for deletion, rub off, or erase
“kill these lines in the President's speech”
tire out completely
“The daily stress of her work is killing her”
cause to cease operating
“kill the engine”
destroy a vitally essential quality of or in
“Eating artichokes kills the taste of all other foods”
the act of terminating a life
Synonyms, antonyms and the broader and narrower relations for kill come from Princeton University’s WordNet. Full sources and licences.
the destruction of an enemy plane or ship or tank or missile
“the pilot reported two kills during the mission”
the body of an animal, or bodies of animals, killed by a person or another animal