WordNet records no synonym and no antonym for insufflate. It is the only member of each of its synsets, which is common for technical, taxonomic and single-sense vocabulary — there is no other English word that means the same thing. The broader and narrower terms below are the useful relations in that case.
Counts are distinct word forms across every sense. A synonym that appears under three senses is counted once here and shown three times below, under each sense it belongs to.
breathe or blow onto as a ritual or sacramental act, especially so as to symbolize the action of the Holy Spirit
treat by blowing a powder or vapor into a bodily cavity
Synonyms, antonyms and the broader and narrower relations for insufflate come from Princeton University’s WordNet. Full sources and licences.