hypostasis has 2 distinct synonyms spread across 2 of its 4 senses. Each sense below keeps its own list, because a synonym belongs to a meaning and not to a word: swapping one sense's substitute into another sense's sentence is how a thesaurus makes writing worse. WordNet records no antonym for it — antonymy is a relation between word forms rather than concepts, so it is deliberately sparse.
Counts are distinct word forms across every sense. A synonym that appears under three senses is counted once here and shown three times below, under each sense it belongs to.
the suppression of a gene by the effect of an unrelated gene
the accumulation of blood in an organ
Synonyms, antonyms and the broader and narrower relations for hypostasis come from Princeton University’s WordNet. Full sources and licences.
any of the three persons of the Godhead constituting the Trinity especially the person of Christ in which divine and human natures are united
(metaphysics) essential nature or underlying reality