hypertonic has no recorded synonym. Each sense below keeps its own list, because a synonym belongs to a meaning and not to a word: swapping one sense's substitute into another sense's sentence is how a thesaurus makes writing worse. Its 2 recorded opposites are hypotonic, isotonic.
Counts are distinct word forms across every sense. A synonym that appears under three senses is counted once here and shown three times below, under each sense it belongs to.
(of living tissue) in a state of abnormally high tension
“hypertonic muscle tissue”
Synonyms, antonyms and the broader and narrower relations for hypertonic come from Princeton University’s WordNet. Full sources and licences.