handless has 7 distinct synonyms spread across 1 of its 2 senses. Each sense below keeps its own list, because a synonym belongs to a meaning and not to a word: swapping one sense's substitute into another sense's sentence is how a thesaurus makes writing worse. Its one recorded opposite is handed.
Counts are distinct word forms across every sense. A synonym that appears under three senses is counted once here and shown three times below, under each sense it belongs to.
without a hand or hands
“a handless war veteran”
lacking physical movement skills, especially with the hands
“a bumbling mechanic”
Synonyms, antonyms and the broader and narrower relations for handless come from Princeton University’s WordNet. Full sources and licences.