fortune has 8 distinct synonyms spread across 3 of its 4 senses. Each sense below keeps its own list, because a synonym belongs to a meaning and not to a word: swapping one sense's substitute into another sense's sentence is how a thesaurus makes writing worse. WordNet records no antonym for it — antonymy is a relation between word forms rather than concepts, so it is deliberately sparse.
Counts are distinct word forms across every sense. A synonym that appears under three senses is counted once here and shown three times below, under each sense it belongs to.
a large amount of wealth or prosperity
an unknown and unpredictable phenomenon that leads to a favorable outcome
“it was my good luck to be there”
your overall circumstances or condition in life (including everything that happens to you)
“whatever my fortune may be”
Synonyms, antonyms and the broader and narrower relations for fortune come from Princeton University’s WordNet. Full sources and licences.