folio has 4 distinct synonyms spread across 2 of its 3 senses. Each sense below keeps its own list, because a synonym belongs to a meaning and not to a word: swapping one sense's substitute into another sense's sentence is how a thesaurus makes writing worse. WordNet records no antonym for it — antonymy is a relation between word forms rather than concepts, so it is deliberately sparse.
Counts are distinct word forms across every sense. A synonym that appears under three senses is counted once here and shown three times below, under each sense it belongs to.
Synonyms, antonyms and the broader and narrower relations for folio come from Princeton University’s WordNet. Full sources and licences.
a book (or manuscript) consisting of large sheets of paper folded in the middle to make two leaves or four pages
“the first folio of Shakespeare's plays”