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efficacious has 2 distinct synonyms spread across 1 of its 2 senses. Each sense below keeps its own list, because a synonym belongs to a meaning and not to a word: swapping one sense's substitute into another sense's sentence is how a thesaurus makes writing worse. Its one recorded opposite is inefficacious.
Counts are distinct word forms across every sense. A synonym that appears under three senses is counted once here and shown three times below, under each sense it belongs to.
marked by qualities giving the power to produce an intended effect
“written propaganda is less efficacious than the habits and prejudices...of the readers”
Synonyms, antonyms and the broader and narrower relations for efficacious come from Princeton University’s WordNet. Full sources and licences.