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drunkenness has 11 distinct synonyms spread across 3 of its 3 senses. Each sense below keeps its own list, because a synonym belongs to a meaning and not to a word: swapping one sense's substitute into another sense's sentence is how a thesaurus makes writing worse. Its one recorded opposite is soberness.
Counts are distinct word forms across every sense. A synonym that appears under three senses is counted once here and shown three times below, under each sense it belongs to.
a temporary state resulting from excessive consumption of alcohol
habitual intoxication; prolonged and excessive intake of alcoholic drinks leading to a breakdown in health and an addiction to alcohol such that abrupt deprivation leads to severe withdrawal symptoms
the act of drinking alcoholic beverages to excess
“drink was his downfall”
Synonyms, antonyms and the broader and narrower relations for drunkenness come from Princeton University’s WordNet. Full sources and licences.