disoblige has 6 distinct synonyms spread across 1 of its 2 senses. Each sense below keeps its own list, because a synonym belongs to a meaning and not to a word: swapping one sense's substitute into another sense's sentence is how a thesaurus makes writing worse. Its one recorded opposite is oblige.
Counts are distinct word forms across every sense. A synonym that appears under three senses is counted once here and shown three times below, under each sense it belongs to.
to cause inconvenience or discomfort to
“Sorry to trouble you, but...”
Synonyms, antonyms and the broader and narrower relations for disoblige come from Princeton University’s WordNet. Full sources and licences.