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differentiate has 12 distinct synonyms spread across 3 of its 6 senses. Each sense below keeps its own list, because a synonym belongs to a meaning and not to a word: swapping one sense's substitute into another sense's sentence is how a thesaurus makes writing worse. Its 2 recorded opposites are integrate, dedifferentiate.
Counts are distinct word forms across every sense. A synonym that appears under three senses is counted once here and shown three times below, under each sense it belongs to.
mark as different
“We distinguish several kinds of maple”
be a distinctive feature, attribute, or trait; sometimes in a very positive sense
“His modesty distinguishes him from his peers”
become different during development
“cells differentiate”
evolve so as to lead to a new species or develop in a way most suited to the environment
become distinct and acquire a different character
Synonyms, antonyms and the broader and narrower relations for differentiate come from Princeton University’s WordNet. Full sources and licences.