creation has 15 distinct synonyms spread across 4 of its 6 senses. Each sense below keeps its own list, because a synonym belongs to a meaning and not to a word: swapping one sense's substitute into another sense's sentence is how a thesaurus makes writing worse. WordNet records no antonym for it — antonymy is a relation between word forms rather than concepts, so it is deliberately sparse.
Counts are distinct word forms across every sense. A synonym that appears under three senses is counted once here and shown three times below, under each sense it belongs to.
the human act of creating
an artifact that has been brought into existence by someone
the event that occurred at the beginning of something
“from its creation the plan was doomed to failure”
the act of starting something for the first time; introducing something new
“she looked forward to her initiation as an adult”
(theology) God's act of bringing the universe into existence
everything that exists anywhere
“they study the evolution of the universe”
Synonyms, antonyms and the broader and narrower relations for creation come from Princeton University’s WordNet. Full sources and licences.