chafe has 20 distinct synonyms spread across 5 of its 8 senses. Each sense below keeps its own list, because a synonym belongs to a meaning and not to a word: swapping one sense's substitute into another sense's sentence is how a thesaurus makes writing worse. WordNet records no antonym for it — antonymy is a relation between word forms rather than concepts, so it is deliberately sparse.
Counts are distinct word forms across every sense. A synonym that appears under three senses is counted once here and shown three times below, under each sense it belongs to.
feel extreme irritation or anger
“He was chafing at her suggestion that he stay at home while she went on a vacation”
soreness and warmth caused by friction
“he had a nasty chafe on his knee”
anger produced by some annoying irritation
Synonyms, antonyms and the broader and narrower relations for chafe come from Princeton University’s WordNet. Full sources and licences.