barrymore has 7 distinct synonyms spread across 5 of its 5 senses. Each sense below keeps its own list, because a synonym belongs to a meaning and not to a word: swapping one sense's substitute into another sense's sentence is how a thesaurus makes writing worse. WordNet records no antonym for it — antonymy is a relation between word forms rather than concepts, so it is deliberately sparse.
Counts are distinct word forms across every sense. A synonym that appears under three senses is counted once here and shown three times below, under each sense it belongs to.
United States actor; son of Maurice Barrymore and Georgiana Barrymore (1882-1942)
United States actress; daughter of Maurice Barrymore and Georgiana Barrymore (1879-1959)
United States actor; son of Maurice Barrymore and Georgiana Barrymore (1878-1954)
United States actress; daughter of John Drew and wife of Maurice Barrymore; mother of Ethel Barrymore and John Barrymore and Lionel Barrymore (1854-1893)
United States actor; husband of Georgiana Emma Barrymore and father of Ethel Barrymore and John Barrymore and Lionel Barrymore (1847-1905)
Synonyms, antonyms and the broader and narrower relations for barrymore come from Princeton University’s WordNet. Full sources and licences.