alien has 10 distinct synonyms spread across 6 of its 6 senses. Each sense below keeps its own list, because a synonym belongs to a meaning and not to a word: swapping one sense's substitute into another sense's sentence is how a thesaurus makes writing worse. WordNet records no antonym for it — antonymy is a relation between word forms rather than concepts, so it is deliberately sparse.
Counts are distinct word forms across every sense. A synonym that appears under three senses is counted once here and shown three times below, under each sense it belongs to.
a form of life assumed to exist outside the Earth or its atmosphere
not contained in or deriving from the essential nature of something
“an economic theory alien to the spirit of capitalism”
Synonyms, antonyms and the broader and narrower relations for alien come from Princeton University’s WordNet. Full sources and licences.