separatist has 3 distinct synonyms spread across 2 of its 2 senses. Each sense below keeps its own list, because a synonym belongs to a meaning and not to a word: swapping one sense's substitute into another sense's sentence is how a thesaurus makes writing worse. WordNet records no antonym for it — antonymy is a relation between word forms rather than concepts, so it is deliberately sparse.
Counts are distinct word forms across every sense. A synonym that appears under three senses is counted once here and shown three times below, under each sense it belongs to.
an advocate of secession or separation from a larger group (such as an established church or a national union)
having separated or advocating separation from another entity or policy or attitude
“a breakaway faction”
Synonyms, antonyms and the broader and narrower relations for separatist come from Princeton University’s WordNet. Full sources and licences.