african-american has 4 distinct synonyms spread across 2 of its 2 senses. Each sense below keeps its own list, because a synonym belongs to a meaning and not to a word: swapping one sense's substitute into another sense's sentence is how a thesaurus makes writing worse. WordNet records no antonym for it — antonymy is a relation between word forms rather than concepts, so it is deliberately sparse.
a person with African ancestry, "Negro" and "Negroid" are archaic and pejorative today
Synonyms, antonyms and the broader and narrower relations for african-american come from Princeton University’s WordNet. Full sources and licences.
Counts are distinct word forms across every sense. A synonym that appears under three senses is counted once here and shown three times below, under each sense it belongs to.
pertaining to or characteristic of Americans of African ancestry
“African-American culture”